N-Benzylpropargylamine

N-Benzylpropargylamine

SCHEMBL669952

C#CCNCc1ccccc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.64
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
MAOA P21397 3/20 0.50
CYP3A4 P08684 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
TSHR P16473 1/20 0.50
MAOB P27338 2/20 0.48
MAPT P10636 2/20 0.48
CHRM2 P08172 1/20 0.48
GAA P10253 1/20 0.48
KDM4E B2RXH2 1/20 0.48
SIGMAR1 Q99720 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Benzylpropargylamine SCHEMBL21995890 0.98 PYCR1 (0.62) PYCR1MEN1KMT2ATDP1MAOA
SCHEMBL13527792 0.88 PYCR1 (0.79) PYCR1MEN1KMT2ATDP1MAOA
Hydrochloric Acid SCHEMBL3168845 0.86 PYCR1 (0.76) PYCR1MEN1KMT2ATDP1MAOA
SCHEMBL8492754 0.83 PYCR1 (0.56) PYCR1MAOAMAOBKDM4E
SCHEMBL18964968 0.80 PYCR1 (0.68) PYCR1MEN1KMT2AMAOAMAOB
SCHEMBL16256844 0.80 PYCR1 (0.68) PYCR1MEN1KMT2AMAOACYP3A4
SCHEMBL333319 0.78 SIGMAR1 (0.55) MAOACYP3A4CYP1A2CYP2D6TSHR
SCHEMBL9045672 0.78 PYCR1 (0.66) PYCR1MEN1KMT2AMAOACYP3A4
SCHEMBL22171304 0.78 PYCR1 (0.60) PYCR1GAAKDM4E
SCHEMBL8831156 0.78 MEN1 (0.64) MEN1KMT2ATDP1MAOAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118406200-A Silver-based hybrid material and preparation method and application thereof 安徽工业大学 2024-07-30 CN claimed
CN-117205970-A Catalyst Ag 4 TNT and its use in catalyzing CO 2 Application in cyclization reaction with propargylamine 安徽大学 2023-12-12 CN claimed
WO-2020223672-A1 FUNCTIONALIZED CYCLIC POLYMERS AND METHODS OF PREPARING SAME UNIVERSITY OF FLORIDA RESEARCHFOUNDATION, INC. (US) 2020-11-05 WO claimed
WO-2020112883-A1 INHIBITION OF LYSINE DEMETHYLASE 1 (LSD1) INDUCES DIFFERENTIATION OF HAIR CELLS MASSACHUSETTS EYE AND EAR INFIRMARY (US) 2020-06-04 WO claimed
CN-102219753-B Triazole compounds as well as preparation method and application thereof UNIV SHANDONG 2012-10-31 CN claimed
CN-102219753-A Triazole compounds as well as preparation method and application thereof UNIV SHANDONG 2011-10-19 CN claimed
EP-1753723-B1 SUBSTITUTED QUINOLINE DERIVATIVES AS MITOTIC KINESIN INHIBITORS NOVARTIS VACCINES & DIAGNOSTIC (US) 2008-08-13 EP claimed
US-4295862-A ANTIKNOCK ACETYLENIC AMINES PHILLIPS PETROLEUM COMPANY (US) 1981-10-20 US claimed
CN-119972191-A Silver-copper alloy nanoparticle with core-shell structure and preparation method and application thereof 华南理工大学 2025-05-13 CN disclosed
CN-118950088-A Mesoporous covalent organic framework anchoring single-atom copper catalyst and preparation method and application thereof 河北大学 2024-11-15 CN disclosed
CN-118406200-A Silver-based hybrid material and preparation method and application thereof 安徽工业大学 2024-07-30 CN disclosed
WO-2024054807-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-03-14 WO disclosed
CN-117205970-A Catalyst Ag 4 TNT and its use in catalyzing CO 2 Application in cyclization reaction with propargylamine 安徽大学 2023-12-12 CN disclosed
CN-113956182-B HDAC/MAO-B dual inhibitor and preparation and application thereof 杭州师范大学 2023-11-17 CN disclosed
US-4295862-A ANTIKNOCK ACETYLENIC AMINES PHILLIPS PETROLEUM COMPANY (US) 1981-10-20 US disclosed
US-4200654-A 3-SUBSTITUTED AMINO-2-HYDROXY-PROPYL ETHERS, SULFIDES, OR SULFONES ABBOTT LABORATORIES (US) 1980-04-29 US disclosed
US-4069377-A Polymerization of ethylenically unsaturated monomers employing secondary-aliphatic α-substituted azoalkanes PENNWALT CORPORATION 1978-01-17 US disclosed
US-4028344-A FOAMING AGENTS, FREE RADICAL INITIATORS PENNWALT CORPORATION (US) 1977-06-07 US disclosed
US-4025502-A POLYMERIZATION CATALYSTS, CURING AGENTS PENNWALT CORPORATION (US) 1977-05-24 US disclosed
US-3992366-A FOR CROSSLINKING PHOTOGRAPHIC GELATINS CIBA-GEIGY AG (CH) 1976-11-16 US disclosed