Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347561 | 0.85 | NPSR1 (0.39) | NPSR1ALDH1A1CYP3A4MAPTCYP2C19 | |
| SCHEMBL28899661 | 0.81 | ALDH1A1 (0.36) | NPSR1ALDH1A1CYP3A4MAPTCYP2C19 | |
| SCHEMBL6695684 | 0.79 | PLAU (0.38) | NPSR1ALDH1A1CYP3A4MAPTCYP2C19 | |
| SCHEMBL6691760 | 0.79 | NPSR1 (0.36) | NPSR1ALDH1A1CYP3A4MAPTCYP2C19 | |
| SCHEMBL28515349 | 0.79 | NPSR1 (0.36) | NPSR1ALDH1A1CYP3A4MAPTCYP2C19 | |
| Bicarbonate SCHEMBL27820467 | 0.77 | NPSR1 (0.41) | NPSR1ALDH1A1CYP3A4MAPTCYP2C19 | |
| SCHEMBL9518724 | 0.75 | NPSR1 (0.43) | NPSR1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL6694934 | 0.75 | MEN1 (0.59) | ALDH1A1L3MBTL1MEN1KMT2AF2 | |
| SCHEMBL8396658 | 0.74 | NPSR1 (0.46) | NPSR1ALDH1A1CYP3A4MAPTCYP2C19 | |
| SCHEMBL5490024 | 0.73 | L3MBTL1 (0.42) | NPSR1ALDH1A1CYP3A4CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3553083-B2 | — | — | 2004-08-11 | — | — | JP | claimed |
| EP-0852494-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-15 | — | — | EP | claimed |
| WO-1997009973-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-03-20 | — | — | WO | claimed |