Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 4/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 2/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014946 | 0.74 | KMT2A (0.42) | KMT2AAKR1B1PPARAPPARGLMNA | |
| SCHEMBL152841 | 0.71 | CYP2C19 (0.46) | KMT2APPARAGAA | |
| SCHEMBL28317536 | 0.71 | SMN1; SMN2 (0.49) | PPARAPPARG | |
| SCHEMBL28857881 | 0.67 | CYP2C19 (0.41) | KMT2APPARAPPARGPPARDLMNA | |
| SCHEMBL3535562 | 0.66 | ALDH1A1 (0.41) | KMT2AAKR1B1GAA | |
| SCHEMBL27176531 | 0.65 | KMT2A (0.39) | KMT2APPARAPPARGLMNAPOLB | |
| SCHEMBL7648071 | 0.65 | ATM (0.36) | PPARGGAAPOLB | |
| SCHEMBL30707911 | 0.65 | KMT2A (0.39) | KMT2APPARAPPARGLMNAPOLB | |
| SCHEMBL8672553 | 0.65 | NPSR1 (0.39) | PPARALMNAPOLB | |
| SCHEMBL2507678 | 0.64 | MAPT (0.45) | KMT2ALMNAPKMGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606056-A2 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | President and Fellows of Harvard College (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024604-A2 | HIGH-VALENT PALLADIUM FLUORIDE COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-02-23 | — | — | WO | disclosed |