Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30319723 | 0.83 | ALDH1A1 (0.83) | ABCG2MAPTCYP3A4ALDH1A1KDM4E | |
| SCHEMBL4826267 | 0.83 | ALDH1A1 (0.83) | ABCG2MAPTCYP3A4ALDH1A1KDM4E | |
| SCHEMBL18106040 | 0.83 | ALDH1A1 (0.83) | ABCG2MAPTCYP3A4ALDH1A1KDM4E | |
| SCHEMBL6698533 | 0.82 | ABCG2 (0.66) | ABCG2ABCB1MAPTCYP3A4ALDH1A1 | |
| SCHEMBL18104369 | 0.81 | ALDH1A1 (0.68) | ABCG2ABCB1MAPTCYP3A4ALDH1A1 | |
| SCHEMBL28823056 | 0.81 | MAPT (0.82) | ABCG2ABCB1MAPTMEN1POLB | |
| SCHEMBL18104378 | 0.81 | ALDH1A1 (0.68) | ABCG2ABCB1MAPTCYP3A4ALDH1A1 | |
| SCHEMBL6723899 | 0.80 | MAOB (0.62) | ABCG2ABCB1MAPTCYP3A4ALDH1A1 | |
| Alpinetin SCHEMBL29580312 | 0.80 | CYP1A1 (0.80) | ABCG2MAPTMEN1POLBKMT2A | |
| Alpinetin SCHEMBL29844118 | 0.80 | CYP1A1 (0.80) | ABCG2MAPTMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147597-A1 | Anti-mycobacterium compositions and methods of preparing and using same | ADVANCED LIFE SCIENCES, INC. | 2004-07-29 | — | — | US | disclosed |
| US-6677350-B1 | ADMINISTERING CHALCONE-LIKE VINYLCARBONYL COMPOUNDS TO PREVENT OR TREAT MYCOBACTERIUM INFECTIONS/TUBERCULOSIS | ADVANCED LIFE SCIENCES, INC. | 2004-01-13 | — | — | US | disclosed |
| EP-1217995-A2 | ANTI-MYCOBACTERIUM COMPOSITIONS AND METHODS OF PREPARING AND USING SAME | Advanced Life Sciences Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021164-A2 | ANTI-MYCOBACTERIUM COMPOSITIONS AND METHODS OF PREPARING AND USING SAME | ADVANCED LIFE SCIENCES, INC. (US) | 2001-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147597-A1 | Anti-mycobacterium compositions and methods of preparing and using same | IMMT, CYP51A1, LSS | ABCG2 12/4885ABCB1 1105/4885MAPT 2468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.