Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | RORB | Q92753 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235811 | 0.92 | TP53 (0.35) | S1PR3DPP4TSHRHSD17B10POLB | |
| SCHEMBL5231048 | 0.90 | TSHR (0.36) | S1PR3DPP4TSHRHSD17B10POLB | |
| SCHEMBL5233036 | 0.89 | RORC (0.37) | S1PR3DPP4ALDH1A1HPGDMAPK1 | |
| SCHEMBL5231638 | 0.88 | TSHR (0.37) | S1PR3DPP4TSHRHSD17B10POLB | |
| SCHEMBL5231951 | 0.88 | POLB (0.34) | DPP4TSHRHSD17B10POLBKDM4E | |
| SCHEMBL5236402 | 0.88 | PGR (0.40) | DPP4HSD17B10KDM4EPGRRORA | |
| Hydrochloric Acid SCHEMBL5235850 | 0.86 | DPP4 (0.41) | DPP4 | |
| SCHEMBL5233701 | 0.86 | TSHR (0.36) | S1PR3DPP4TSHRHSD17B10KDM4E | |
| SCHEMBL5275959 | 0.86 | RORA (0.37) | DPP4TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL5232653 | 0.86 | MAPT (0.36) | S1PR3TSHRHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082607-A1 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082607-A1 | Fused heterocyclic compounds | DPP7, DPP4, METAP1 | S1PR3 4779/4885DPP4 2/4885TSHR 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.