SCHEMBL14906253

SCHEMBL14906253

CC(C)C(NC(=O)C(N)CCCCN)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.55
DPP8 Q6V1X1 6/20 0.51
DPP9 Q86TI2 6/20 0.51
DPP7 Q9UHL4 5/20 0.51
GNAI3 P08754 1/20 0.48
GNAO1 P09471 1/20 0.48
GNAI1 P63096 1/20 0.48
ERAP2 Q6P179 2/20 0.47
DPP4 P27487 3/20 0.46
MMP2 P08253 1/20 0.42
CPB2 Q96IY4 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
RNPEP Q9H4A4 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LNPEP Q9UIQ6 2/20 0.40
FOLH1 Q04609 1/20 0.40
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31722025 1.00 GSR (0.55) GSRDPP8DPP9DPP7GNAI3
SCHEMBL28000252 1.00 GSR (0.55) GSRDPP8DPP9DPP7GNAI3
SCHEMBL22612668 1.00 GSR (0.55) GSRDPP8DPP9DPP7GNAI3
SCHEMBL30569498 0.95 DPP8 (0.50) GSRDPP8DPP9DPP7GNAI3
SCHEMBL6700441 0.90 GSR (0.45) GSRDPP8DPP9DPP7GNAI3
SCHEMBL30728888 0.90 NMT1 (0.46) GSRDPP8DPP9DPP7GNAI3
SCHEMBL6700436 0.90 GSR (0.45) GSRDPP8DPP9DPP7GNAI3
SCHEMBL30123089 0.90 GSR (0.47) GSRDPP8DPP9DPP7GNAI3
SCHEMBL32670655 0.89 GSR (0.44) GSRDPP8DPP9DPP7GNAI3
SCHEMBL29776755 0.89 GSR (0.44) GSRDPP8DPP9DPP7ERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295713-A1 COMPOSITIONS AND METHODS FOR IMPROVING SKIN HEALTH AND FOR THE TREATMENT AND PREVENTION OF DISEASES, DISORDERS AND CONDITIONS ASSOCIATED WITH PATHOGENIC MICROBES DERMBIONT, INC. 2025-09-25 US disclosed
CN-118866397-A UPLC-Q-Exactive/MS-based donkey-hide gelatin blood-replenishing granule for treating mechanism metabonomics analysis method and application thereof 九芝堂股份有限公司 2024-10-29 CN disclosed
US-12064459-B2 Compositions and methods for improving skin health and for the treatment and prevention of diseases, disorders and conditions associated with pathogenic microbes DERMBIONT, INC. (US) 2024-08-20 US disclosed
US-20230124955-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-04-20 US disclosed
EP-4074694-A1 AMINO ACID-, PEPTIDE- AN POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AN USES THEREOF Massachusetts Institute Of Technology (US) 2022-10-19 EP disclosed
US-20220160617-A1 COMPOSITIONS AND METHODS FOR IMPROVING SKIN HEALTH AND FOR THE TREATMENT AND PREVENTION OF DISEASES, DISORDERS AND CONDITIONS ASSOCIATED WITH PATHOGENIC MICROBES DERMBIONT, INC. 2022-05-26 US disclosed
US-20210386802-A1 COMPOSITIONS AND METHODS FOR IMPROVING SKIN HEALTH AND FOR THE TREATMENT AND PREVENTION OF DISEASES, DISORDERS AND CONDITIONS ASSOCIATED WITH PATHOGENIC MICROBES DERMBIONT, INC. 2021-12-16 US disclosed
US-20210361725-A1 COMPOSITIONS AND METHODS FOR IMPROVING SKIN HEALTH AND FOR THE TREATMENT AND PREVENTION OF DISEASES, DISORDERS AND CONDITIONS ASSOCIATED WITH PATHOGENIC MICROBES DERMBIONT, INC. 2021-11-25 US disclosed
US-11040077-B2 Compositions and methods for improving skin health and for the treatment and prevention of diseases, disorders and conditions associated with pathogenic microbes DERMBIONT, INC. (US) 2021-06-22 US disclosed
CN-105683390-B HbA1c measurement method using amadoriase acting on glycosylated peptide 龟甲万株式会社 2021-02-26 CN disclosed
US-10682374-B2 Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof MASSACHUSETTS INTSTITUTE OF TECHNOLOGY (US) 2020-06-16 US disclosed
US-20190076462-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2019-03-14 US disclosed
US-20180036333-A9 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-02-08 US disclosed
US-20180036333-A9 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-02-08 US disclosed
US-20170165290-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-06-15 US disclosed
US-20170165290-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-06-15 US disclosed
US-9512073-B2 Amino acid-, peptide-and polypeptide-lipids, isomers, compositions, and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-12-06 US disclosed
CN-104470925-A Imidazotriazinecarbonitriles useful as kinase inhibitors BRISTOL MYERS SQUIBB CO 2015-03-25 CN disclosed
US-20130158021-A1 AMINO ACID-, PEPTIDE-AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-06-20 US disclosed
WO-2013063468-A1 AMINO ACID DERIVATES FUNCTIONALIZED ON THE N- TERMINAL CAPABLE OF FORMING DRUG INCAPSULATING MICROSPHERES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230124955-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 GSR 1896/4885DPP8 484/4885DPP9 356/4885
US-20170165290-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 GSR 1896/4885DPP8 484/4885DPP9 356/4885
US-20190076462-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 GSR 1896/4885DPP8 484/4885DPP9 356/4885
US-20180036333-A9 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 GSR 1896/4885DPP8 484/4885DPP9 356/4885
US-20130158021-A1 AMINO ACID-, PEPTIDE-AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 GSR 1896/4885DPP8 484/4885DPP9 356/4885
US-10682374-B2 Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof APLNR, NPPA, ARGLU1 GSR 1896/4885DPP8 484/4885DPP9 356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.