Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803507 | 0.95 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL16005507 | 0.93 | LMNA (0.62) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL8587079 | 0.93 | LMNA (0.62) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL28171439 | 0.93 | LMNA (0.62) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL3480724 | 0.93 | LMNA (0.62) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL16005163 | 0.93 | LMNA (0.62) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL8584485 | 0.93 | LMNA (0.62) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL16005044 | 0.93 | LMNA (0.62) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL21919473 | 0.92 | ALDH1A1 (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL258876 | 0.92 | ALDH1A1 (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002265-A1 | RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF | BEIJING INCREASE INNOVATIVE DRUG CO., LTD (CN) | 2022-01-06 | — | — | US | disclosed |
| EP-3878846-A1 | RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF | Beijing Increase Innovative Drug Co., Ltd. (CN) | 2021-09-15 | — | — | EP | disclosed |
| EP-2606022-A2 | NOVEL BENZOQUINONE DERIVATIVES AND USE THEREOF AS MODULATORS OF MITOCHONDRIAL FUNCTION | Santhera Pharmaceuticals (Schweiz) AG (CH) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012022467-A2 | NOVEL BENZOQUINONE DERIVATIVES AND USE THEREOF AS MODULATORS OF MITOCHONDRIAL FUNCTION | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002265-A1 | RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF | ROCK1, RHOA, ROCK2 | SMN1; SMN2 4404/4885LMNA 1555/4885ALDH1A1 4142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.