Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700784 | 0.82 | PRKCI (0.60) | HDAC1CYP2A6CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL6851763 | 0.76 | HDAC1 (0.41) | HDAC1CYP2A6CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL10160999 | 0.76 | HDAC1 (0.43) | HDAC1CYP2A6CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL6698000 | 0.76 | CYP2A6 (0.56) | HDAC1CYP2A6CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL10130682 | 0.71 | HDAC1 (0.40) | HDAC1CYP2A6CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL6877257 | 0.70 | HDAC1 (0.42) | HDAC1CYP2A6CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL27612769 | 0.69 | HDAC1 (0.45) | HDAC1CYP2A6CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL13514034 | 0.68 | SLC5A2 (0.37) | HDAC1CYP2A6CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL27594383 | 0.67 | HDAC1 (0.40) | HDAC1CYP2A6CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL11996764 | 0.66 | HDAC1 (0.48) | HDAC1SLC5A2KDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014687-A1 | Macrolide antibacterial compounds | ABBOTT LABORATORIES | 2004-01-22 | — | — | US | claimed |
| US-20040014687-A1 | Macrolide antibacterial compounds | ABBOTT LABORATORIES | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014687-A1 | Macrolide antibacterial compounds | MRPL21, NOP2, PIGS | HDAC1 79/4885CYP2A6 122/4885CYP2C19 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.