Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 8/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700780 | 0.82 | HDAC1 (0.47) | PRKCICYP2A6CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL10160999 | 0.79 | HDAC1 (0.43) | PRKCICYP2A6CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL6698000 | 0.76 | CYP2A6 (0.56) | CYP2A6CYP2D6CYP2C19CYP2C9HDAC1 | |
| SCHEMBL10130682 | 0.75 | HDAC1 (0.40) | PRKCICYP2A6CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL3607664 | 0.75 | CYP2A6 (1.00) | PRKCICYP2A6CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL2368653 | 0.74 | PRKCI (0.69) | PRKCICYP2A6CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL6851763 | 0.73 | HDAC1 (0.41) | PRKCICYP2A6CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL13514034 | 0.71 | SLC5A2 (0.37) | PRKCICYP2A6CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL25078434 | 0.70 | LTA4H (0.58) | PRKCICYP2A6CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL6877257 | 0.70 | HDAC1 (0.42) | CYP2A6CYP2D6CYP2C19CYP2C9HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014687-A1 | Macrolide antibacterial compounds | ABBOTT LABORATORIES | 2004-01-22 | — | — | US | claimed |
| US-20040014687-A1 | Macrolide antibacterial compounds | ABBOTT LABORATORIES | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014687-A1 | Macrolide antibacterial compounds | MRPL21, NOP2, PIGS | PRKCI 4382/4885CYP2A6 122/4885CYP2D6 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.