Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.60 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.60 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28808281 | 0.98 | GNAI3 (0.63) | GNAI3GNAO1GNAI1POLBALDH1A1 | |
| SCHEMBL16364960 | 0.89 | GNAI3 (0.49) | GNAI3GNAO1GNAI1POLBALDH1A1 | |
| SCHEMBL6135546 | 0.87 | GNAI3 (0.69) | GNAI3GNAO1GNAI1POLBALDH1A1 | |
| SCHEMBL3987516 | 0.85 | — | — | |
| SCHEMBL16908227 | 0.82 | GNAI3 (0.58) | GNAI3GNAO1GNAI1POLBALDH1A1 | |
| SCHEMBL22124441 | 0.82 | GNAI3 (0.58) | GNAI3GNAO1GNAI1POLBALDH1A1 | |
| SCHEMBL2262712 | 0.82 | GNAI3 (0.58) | GNAI3GNAO1GNAI1POLBALDH1A1 | |
| SCHEMBL1438745 | 0.82 | GNAI3 (0.73) | GNAI3GNAO1GNAI1POLBALDH1A1 | |
| SCHEMBL19301621 | 0.81 | NAAA (0.52) | ALDH1A1SMN1; SMN2LMNANAAAKMT2A | |
| SCHEMBL15739433 | 0.81 | NAAA (0.56) | ALDH1A1SMN1; SMN2LMNANAAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819328-A | Memantine urea derivative, preparation method thereof and application thereof in preparing medicine for treating soluble epoxide hydrolase mediated diseases | 沈阳药科大学 | 2023-03-21 | — | — | CN | claimed |
| US-20200109167-A1 | SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | UNIV MICHIGAN REGENTS (US) | 2020-04-09 | — | — | US | claimed |
| EP-3601245-A1 | SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | The Regents of The University of Michigan (US) | 2020-02-05 | — | — | EP | claimed |
| WO-2018183411-A1 | SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-10-04 | — | — | WO | claimed |
| EP-0213337-B1 | 4-CYANOPIPERIDINE DERIVATIVES, PREPARATION AND USE THEREOF | Eisai Co., Ltd. (JP) | 1991-05-15 | — | — | EP | claimed |
| WO-2025051241-A1 | MACROCYCLIC COMPOUND AND ANTIBODY-DRUG CONJUGATE THEREOF | 劲方医药科技(上海)股份有限公司 | 2025-03-13 | — | — | WO | disclosed |
| US-12012467-B2 | Small molecule DCN1 inhibitors and therapeutic methods using the same | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-18 | — | — | US | disclosed |
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-115819328-A | Memantine urea derivative, preparation method thereof and application thereof in preparing medicine for treating soluble epoxide hydrolase mediated diseases | 沈阳药科大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| US-20210340121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-11-04 | — | — | US | disclosed |
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |
| US-20110152235-A1 | Aminopyrimidine Kinase Inhibitors | Jasco Pharmaceuticals, LLC (US) | 2011-06-23 | — | — | US | disclosed |
| WO-2002081466-A1 | PRODRUGS OF 3-(PYRROL-2-YLMETHYLIDENE)-2-INDOLINONE DERIVATIVES | SUGEN, INC. (US) | 2002-10-17 | — | — | WO | disclosed |
| US-4721788-A | 4-cyanopiperidine derivatives | EISAI CO., LTD. (JP) | 1988-01-26 | — | — | US | disclosed |
| US-4721788-A | 4-cyanopiperidine derivatives | EISAI CO., LTD. (JP) | 1988-01-26 | — | — | US | disclosed |
| EP-0213337-A1 | 4-cyanopiperidine derivatives, preparation and use thereof | Eisai Co., Ltd. (JP) | 1987-03-11 | — | — | EP | disclosed |
| EP-0213337-A1 | 4-cyanopiperidine derivatives, preparation and use thereof | Eisai Co., Ltd. (JP) | 1987-03-11 | — | — | EP | disclosed |
| US-4243666-A | HYPOTENSIVE AGENTS | PFIZER INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4117140-A | BRONCHODILATING PIPERIDINOETHYL BENZOPYRANOPYRIDINONES | BROWN RICHARD E | 1978-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | GRIN2B, GRIN2A, GRIN3B | GNAI3 602/4885GNAO1 200/4885GNAI1 384/4885 |
| US-20200109167-A1 | SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | DCUN1D2, CLN6, CAPNS1 | GNAI3 2092/4885GNAO1 1681/4885GNAI1 1445/4885 |
| US-12012467-B2 | Small molecule DCN1 inhibitors and therapeutic methods using the same | DCUN1D2, CLN6, CAPNS1 | GNAI3 2092/4885GNAO1 1681/4885GNAI1 1445/4885 |
| US-20110152235-A1 | Aminopyrimidine Kinase Inhibitors | PIM1, PIM2, PIM3 | GNAI3 2677/4885GNAO1 3988/4885GNAI1 2124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.