Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.69 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.69 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.69 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670169 | 0.87 | GNAI3 (0.60) | GNAI3GNAO1GNAI1NAAAPOLB | |
| Hydrochloric Acid SCHEMBL28808281 | 0.85 | GNAI3 (0.63) | GNAI3GNAO1GNAI1NAAAPOLB | |
| SCHEMBL4555068 | 0.84 | GNAI3 (0.94) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| SCHEMBL6017191 | 0.83 | GNAI3 (0.97) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| SCHEMBL19309524 | 0.82 | GNAI3 (0.64) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| SCHEMBL1438748 | 0.82 | GNAI3 (0.84) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| SCHEMBL13712654 | 0.81 | NAAA (0.69) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| Hydrochloric Acid SCHEMBL20542952 | 0.81 | GNAI3 (1.00) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| SCHEMBL20142152 | 0.81 | GNAI3 (0.63) | GNAI3GNAO1GNAI1NAAAEPHX1 | |
| SCHEMBL3517689 | 0.81 | NAAA (0.52) | GNAI3GNAO1GNAI1NAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100121048-A1 | Cyclic Amine Compound and Use Thereof for the Prophylaxis or Treatment of Hypertension | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-13 | — | — | US | disclosed |
| WO-2007094513-A2 | CYCLIC AMINE COMPOUND AND USE THEREOF FOR THE PROPHYLAXIS OR TREATMENT OF HYPERTENSION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-23 | — | — | WO | disclosed |
| EP-1591462-A2 | Temperature-responsive polymer compound and process for producing the same | Amersham Biosciences KK (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-6956077-B1 | Temperature-responsive polymer compound and process for producing the same | AMERSHAM BIOSCIENCES KK (JP) | 2005-10-18 | — | — | US | disclosed |
| US-20050224415-A1 | Temperature-responsive polymer compound and process for producing the same | AMERSHAM BIOSCIENCES KK | 2005-10-13 | — | — | US | disclosed |
| EP-1153049-B1 | TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME | AMERSHAM BIOSCIENCES KK (JP) | 2005-08-10 | — | — | EP | disclosed |
| EP-1153049-A1 | TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME | Amersham Pharmacia Biotech K.K. (JP) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000044800-A1 | TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME | AMERSHAM PHARMACIA BIOTECH K.K. (JP) | 2000-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121048-A1 | Cyclic Amine Compound and Use Thereof for the Prophylaxis or Treatment of Hypertension | REN, AGTR1, AGTR2 | GNAI3 2906/4885GNAO1 1994/4885GNAI1 2722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.