Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660285 | 0.92 | MTNR1A (0.39) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL28728329 | 0.86 | TSHR (0.44) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL28846188 | 0.76 | TSHR (0.41) | TSHRLMNAMAPK1L3MBTL1AKT1 | |
| SCHEMBL10606928 | 0.76 | CYP1B1 (0.40) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL22723000 | 0.75 | SMN1; SMN2 (0.38) | LMNAMAPK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL30827272 | 0.75 | KDM1A (0.39) | LMNAMAPK1HTTL3MBTL1ATM | |
| SCHEMBL7877634 | 0.74 | LTA4H (0.43) | TSHRLMNAL3MBTL1CES2CES1 | |
| SCHEMBL17239095 | 0.73 | ATM (0.36) | TSHRLMNAMAPK1HTTL3MBTL1 | |
| SCHEMBL19524505 | 0.73 | KMT2A (0.40) | TSHRLMNAMAPK1L3MBTL1ATM | |
| SCHEMBL11880188 | 0.73 | LTA4H (0.43) | TSHRLMNAMAPK1ALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790909-B2 | INITIATOR FUNCTIONS SUITABLE FOR CATIONIC POLYMERIZATION INTO THE MACROINITIATOR. EXAMPLES OF SUCH INTERESTING INITIATOR FUNCTIONS ARE GROUPS CONTAINING HALOGEN OR SULFONYL CHLORIDE | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-14 | — | — | US | disclosed |
| US-20040024145-A1 | Graft copolymers, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |