Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14956511 | 0.85 | LMNA (0.46) | ATMLMNAKMT2AMEN1MAPT | |
| SCHEMBL660285 | 0.79 | MTNR1A (0.39) | ATMLMNAKMT2ANPC1MEN1 | |
| SCHEMBL30827272 | 0.78 | KDM1A (0.39) | ATMLMNAKMT2ANPC1MEN1 | |
| SCHEMBL17239063 | 0.77 | TSHR (0.41) | LMNAKMT2ANPC1MEN1MAPT | |
| SCHEMBL19524505 | 0.76 | KMT2A (0.40) | ATMLMNAKMT2ANPC1MEN1 | |
| SCHEMBL1274897 | 0.74 | MEN1 (0.42) | LMNAKMT2ANPC1MEN1MAPT | |
| SCHEMBL28846188 | 0.74 | TSHR (0.41) | ATMLMNAKMT2ANPC1MEN1 | |
| SCHEMBL4651907 | 0.74 | MEN1 (0.42) | LMNAKMT2ANPC1MEN1MAPT | |
| SCHEMBL11086524 | 0.73 | ALDH1A1 (0.41) | ATMLMNAKMT2ANPC1MEN1 | |
| SCHEMBL6701706 | 0.73 | PDE4A (0.36) | ATMLMNAKMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512272-B2 | Curable composition containing silicone, and cured product thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2016-12-06 | — | — | US | disclosed |
| US-20150322211-A1 | Curable Composition Containing Silicone, and Cured Product Thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2015-11-12 | — | — | US | disclosed |