Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703807 | 0.90 | PLTP (0.39) | TRPV4MAPTTP53LMNASAE1 | |
| SCHEMBL6698972 | 0.89 | TRPV4 (0.34) | TRPV4MAPTTP53LMNASAE1 | |
| SCHEMBL6702286 | 0.85 | MAPT (0.32) | MAPTTP53LMNASAE1HTT | |
| SCHEMBL1008694 | 0.84 | TRPV4 (0.36) | TRPV4MAPTTP53LMNASAE1 | |
| SCHEMBL29403637 | 0.84 | TRPV4 (0.36) | TRPV4MAPTTP53LMNASAE1 | |
| SCHEMBL6700555 | 0.82 | TRPV4 (0.35) | TRPV4MAPTSAE1NPC1CHRM4 | |
| SCHEMBL7688594 | 0.82 | TRPV4 (0.34) | TRPV4MAPTTP53LMNASAE1 | |
| SCHEMBL226080 | 0.82 | TRPV4 (0.32) | TRPV4TP53PI4KB | |
| Water SCHEMBL7685985 | 0.82 | TRPV4 (0.33) | TRPV4MAPTTP53LMNASAE1 | |
| Trifluoroacetic Acid SCHEMBL226079 | 0.81 | TRPV4 (0.34) | TRPV4MAPTTP53LMNASAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |