Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | GRM8 | O00222 | 2/20 | 0.32 |
| ▸ | GRM6 | O15303 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669430 | 0.78 | CYP2C19 (0.31) | CYP2C19HSD11B1 | |
| SCHEMBL1155589 | 0.75 | THRB (0.35) | — | |
| SCHEMBL59598 | 0.73 | CYP2C19 (0.38) | GRM2GRM3GRM4CYP2C19GRM8 | |
| SCHEMBL6276924 | 0.73 | GRM4 (0.35) | GRM2GRM3GRM4CYP2C19GRM8 | |
| SCHEMBL8075382 | 0.73 | THRB (0.33) | — | |
| SCHEMBL2939527 | 0.72 | GRM2 (0.46) | GRM2GRM3GRM4CYP2C19GRM8 | |
| SCHEMBL7135246 | 0.72 | GRM2 (0.46) | GRM2GRM3GRM4CYP2C19GRM8 | |
| Hydrochloric Acid SCHEMBL6363451 | 0.71 | GRM4 (0.34) | GRM2GRM3GRM4CYP2C19GRM8 | |
| SCHEMBL6565000 | 0.71 | — | — | |
| SCHEMBL28434000 | 0.71 | GRM2 (0.44) | GRM2GRM3GRM4CYP2C19GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229045-A1 | applying mixtures of isocyanate, carbonyl, epoxide, anhydride and/or carbonate compounds or polymers, and adipic dihydrazine or carbodihydrazide on substrates, then heating to form nonyellowing coatings having pot life | STAHL INTERNATIONAL B.V. (NL) | 2004-11-18 | — | — | US | disclosed |