Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13513405 | 1.00 | NPC1 (0.56) | NPC1MEN1KMT2AATMHSP90AA1 | |
| SCHEMBL11371745 | 0.91 | CA12 (0.46) | NPC1MEN1KMT2AATMHSP90AA1 | |
| SCHEMBL15472768 | 0.88 | NPC1 (0.51) | NPC1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL8172221 | 0.86 | LMNA (0.59) | NPC1MEN1KMT2AATMHSP90AA1 | |
| SCHEMBL1970298 | 0.86 | KMT2A (0.44) | NPC1MEN1KMT2AGAARAB9A | |
| SCHEMBL13513360 | 0.85 | ALDH1A1 (0.51) | NPC1MEN1KMT2AATMHSP90AA1 | |
| SCHEMBL1965917 | 0.84 | SMN1; SMN2 (0.51) | MEN1KMT2AATMGAAALDH1A1 | |
| SCHEMBL11156933 | 0.83 | KDM4E (0.49) | NPC1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9661113 | 0.83 | NPC1 (0.53) | NPC1MEN1KMT2AGAAPIN1 | |
| SCHEMBL1340269 | 0.83 | KMT2A (0.48) | MEN1KMT2AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117904087-A | Halohydrin dehalogenase mutant and application thereof in preparation of chiral oxazolidinone | 中国科学院天津工业生物技术研究所 | 2024-04-19 | — | — | CN | claimed |
| US-12227507-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2025-02-18 | — | — | US | disclosed |
| CN-114555604-B | Pharmaceutical compounds | 辉瑞公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118684657-A | 1, 2-Benzopyrone derivative, preparation method and medical application thereof | 中国药科大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-117904087-A | Halohydrin dehalogenase mutant and application thereof in preparation of chiral oxazolidinone | 中国科学院天津工业生物技术研究所 | 2024-04-19 | — | — | CN | disclosed |
| CN-117285516-A | Dehydrogenated phenyl achyranthis statin compound, preparation method and application thereof | 大连万众益生大健康有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-116023202-A | Synthetic method of alpha-chlorarone derivative | 西南大学 | 2023-04-28 | — | — | CN | disclosed |
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
| US-20220324873-A1 | PHARMACEUTICAL COMPOUNDS | PFIZER INC. | 2022-10-13 | — | — | US | disclosed |
| EP-0074130-B1 | NEW IMIDAZOLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON S.p.A. (IT) | 1990-09-19 | — | — | EP | disclosed |
| US-4663347-A | ANTIINFLAMMATORY, ANTIALLERGENS, CARDIOVASCULAR | MERCK FROSST CANADA, INC. (CA) | 1987-05-05 | — | — | US | disclosed |
| US-4560696-A | Analgesic, antipyretic or anti-inflammatory imidazole compounds | ZAMBON S.P.A. (IT) | 1985-12-24 | — | — | US | disclosed |
| EP-0146243-A1 | Lipoxygenase inhibitors | MERCK FROSST CANADA INC. (CA) | 1985-06-26 | — | — | EP | disclosed |
| EP-0044119-B1 | PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE | STAMICARBON B.V. (NL) | 1985-05-29 | — | — | EP | disclosed |
| US-4435552-A | COORDINATION CATALYST CONTAINING HALOACYL COMPOUND | STAMICARBON B.V. (NL) | 1984-03-06 | — | — | US | disclosed |
| EP-0074130-A2 | New imidazole compounds, process for the preparation thereof and pharmaceutical compositions containing them | ZAMBON S.p.A. (IT) | 1983-03-16 | — | — | EP | disclosed |
| EP-0044119-A2 | Process for the preparation of copolymers of ethylene with at least one other 1-alkene | STAMICARBON B.V. (NL) | 1982-01-20 | — | — | EP | disclosed |
| US-4275200-A | CONDENSATION OF CARBAMIC ESTERS WITH X-HALOGEN CARBONYL COMPOUNDS | AGFA-GEVAERT, A.G. (DE) | 1981-06-23 | — | — | US | disclosed |
| US-4059447-A | Photographic material containing oxazolinone-2 couplers | AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12227507-B2 | Pharmaceutical compounds | CHRNA6, GABRA6, CHRNA7 | NPC1 484/4885MEN1 3324/4885KMT2A 3557/4885 |
| US-11634425-B2 | Pharmaceutical compounds | GABRA6, CHRNA6, CNR1 | NPC1 605/4885MEN1 3338/4885KMT2A 3408/4885 |
| US-20220324873-A1 | PHARMACEUTICAL COMPOUNDS | GABRA6, CNR1, CHRNA6 | NPC1 547/4885MEN1 2661/4885KMT2A 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.