Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1093747 | 0.77 | ADORA2A (0.47) | PDPK1LOXL2ADORA1ADORA2ACYP2A6 | |
| SCHEMBL29608350 | 0.77 | ADORA2A (0.47) | PDPK1LOXL2ADORA1ADORA2ACYP2A6 | |
| Hydrochloric Acid SCHEMBL5692845 | 0.76 | ADORA2A (0.46) | PDPK1LOXL2ADORA1ADORA2ACYP2A6 | |
| SCHEMBL27997605 | 0.76 | CA2 (0.43) | PDPK1LOXL2ADORA1ADORA2AENPP3 | |
| Hydrochloric Acid SCHEMBL5692830 | 0.76 | ADORA2A (0.46) | PDPK1LOXL2ADORA1ADORA2ACYP2A6 | |
| SCHEMBL4723106 | 0.74 | KDM4E (0.42) | ADORA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL28816427 | 0.74 | LOXL2 (0.45) | PDPK1LOXL2ADORA1ADORA2ACYP2A6 | |
| SCHEMBL3838065 | 0.74 | ALDH1A1 (0.39) | PDPK1LOXL2ADORA1ADORA2AHSP90AA1 | |
| SCHEMBL30130504 | 0.74 | ALDH1A1 (0.39) | PDPK1LOXL2ADORA1ADORA2AHSP90AA1 | |
| SCHEMBL27685705 | 0.74 | ADORA2A (0.44) | PDPK1LOXL2ADORA1ADORA2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112783-A1 | NEW USE IV | BIOVITRUM AB (SE) | 2004-12-29 | — | — | WO | claimed |
| WO-2004112783-A1 | NEW USE IV | BIOVITRUM AB (SE) | 2004-12-29 | — | — | WO | disclosed |