Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087093 | 0.95 | MAPT (0.39) | RXFP1MAPTTP53ALDH1A1POLB | |
| SCHEMBL6699878 | 0.93 | PTGDR2 (0.35) | RXFP1MAPTTP53ALDH1A1POLB | |
| SCHEMBL6702247 | 0.87 | RXFP1 (0.37) | RXFP1MAPTTP53ALDH1A1POLB | |
| SCHEMBL6702244 | 0.83 | RXFP1 (0.37) | RXFP1MAPTTP53ALDH1A1POLB | |
| SCHEMBL7091394 | 0.83 | MAPT (0.34) | RXFP1MAPTTP53ALDH1A1POLB | |
| SCHEMBL6704419 | 0.82 | MAPT (0.39) | RXFP1MAPTTP53ALDH1A1LMNA | |
| SCHEMBL6699876 | 0.80 | PTGDR2 (0.35) | RXFP1MAPTTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL6704678 | 0.78 | MAPT (0.39) | RXFP1MAPTTP53ALDH1A1LMNA | |
| SCHEMBL27581733 | 0.78 | TRPV4 (0.34) | MAPTTP53ALDH1A1SMN1; SMN2PTGDR2 | |
| SCHEMBL6702802 | 0.78 | GAA (0.39) | MAPTTP53ALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |