Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087093 | 0.88 | MAPT (0.39) | MAPTLMNATP53ALDH1A1NFKB1 | |
| SCHEMBL6703725 | 0.86 | MAPT (0.34) | MAPTLMNATP53ALDH1A1F10 | |
| SCHEMBL6703723 | 0.83 | F10 (0.36) | MAPTLMNATP53ALDH1A1F10 | |
| SCHEMBL7086912 | 0.83 | SCD (0.36) | MAPTTP53ALDH1A1F10POLB | |
| SCHEMBL6702250 | 0.83 | RXFP1 (0.37) | MAPTLMNATP53ALDH1A1NFKB1 | |
| SCHEMBL6702802 | 0.82 | GAA (0.39) | MAPTLMNATP53ALDH1A1POLB | |
| SCHEMBL6703653 | 0.81 | MEN1 (0.37) | MAPTLMNATP53ALDH1A1F10 | |
| SCHEMBL6704667 | 0.78 | TRPV4 (0.33) | MAPTLMNATP53ALDH1A1RXFP1 | |
| SCHEMBL7679717 | 0.78 | MEN1 (0.40) | MAPTLMNATP53ALDH1A1F10 | |
| SCHEMBL6703652 | 0.78 | MEN1 (0.38) | MAPTLMNATP53ALDH1A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |