Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.67 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702319 | 1.00 | DPP4 (0.67) | DPP4DPP7ALDH1A1DPP8SMN1; SMN2 | |
| SCHEMBL6702249 | 0.85 | DPP4 (0.78) | DPP4DPP7ALDH1A1DPP8POLB | |
| SCHEMBL6702254 | 0.85 | DPP4 (0.78) | DPP4DPP7ALDH1A1DPP8POLB | |
| SCHEMBL6594019 | 0.80 | DPP4 (1.00) | DPP4DPP7DPP8 | |
| SCHEMBL6697154 | 0.74 | ALDH1A1 (0.63) | DPP4DPP7ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29395449 | 0.72 | POLB (0.63) | DPP4DPP7ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7994938 | 0.71 | POLB (0.62) | DPP4DPP7ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5360157 | 0.70 | DPP4 (0.73) | DPP4DPP7DPP8 | |
| SCHEMBL5360154 | 0.70 | DPP4 (0.73) | DPP4DPP7DPP8 | |
| SCHEMBL7233175 | 0.70 | GAA (0.65) | DPP4ALDH1A1SMN1; SMN2POLBMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | DPP4 1/4885DPP7 4/4885ALDH1A1 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.