Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705000 | 0.90 | MAPT (0.61) | MAPTALDH1A1GAAALOX15HSD17B10 | |
| SCHEMBL6703990 | 0.86 | ALDH1A1 (0.51) | MAPTALDH1A1GAAALOX15HSD17B10 | |
| SCHEMBL6697526 | 0.85 | MAPT (0.52) | MAPTALDH1A1GAAALOX15KDM4E | |
| SCHEMBL6701909 | 0.84 | MAPT (0.59) | MAPTALDH1A1GAAALOX15HSD17B10 | |
| SCHEMBL6704568 | 0.83 | KIF11 (0.44) | MAPTALDH1A1GAAALOX15HSD17B10 | |
| SCHEMBL6627881 | 0.82 | ALDH1A1 (0.45) | MAPTALDH1A1GAAALOX15HSD17B10 | |
| SCHEMBL6703684 | 0.79 | ALDH1A1 (0.46) | MAPTALDH1A1GAAALOX15HSD17B10 | |
| SCHEMBL6704844 | 0.77 | MAPT (0.51) | MAPTALDH1A1GAAALOX12MEN1 | |
| SCHEMBL6704507 | 0.77 | ALDH1A1 (0.46) | MAPTALDH1A1GAAALOX15HSD17B10 | |
| SCHEMBL6699680 | 0.77 | ALDH1A1 (0.54) | MAPTALDH1A1GAAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116417-A1 | Thiohydantoins and use thereof for treating diabetes | LABORATOIRES FOURNIER SA (FR) | 2004-06-17 | — | — | US | disclosed |