Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702824 | 0.86 | KIF11 (0.53) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6704097 | 0.86 | KIF11 (0.53) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6704568 | 0.80 | KIF11 (0.44) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6627356 | 0.80 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6703155 | 0.79 | ALDH1A1 (0.52) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6702569 | 0.77 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6704444 | 0.77 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6703556 | 0.76 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6699022 | 0.76 | KIF11 (0.54) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6702073 | 0.76 | RAD51 (0.49) | MAPTALDH1A1MEN1KMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116417-A1 | Thiohydantoins and use thereof for treating diabetes | LABORATOIRES FOURNIER SA (FR) | 2004-06-17 | — | — | US | disclosed |