Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HK1 | P19367 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705251 | 0.94 | SAE1 (0.34) | CHRM4MAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL6704665 | 0.89 | CHRM4 (0.33) | CHRM4MAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL6702438 | 0.89 | MAPT (0.38) | CHRM4MAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL6703993 | 0.88 | MAPT (0.42) | CHRM4MAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL7679774 | 0.87 | SAE1 (0.35) | CHRM4SAE1UBA2TP53ROCK2 | |
| SCHEMBL6700553 | 0.86 | CHRM4 (0.33) | CHRM4MAPTALDH1A1SAE1UBA2 | |
| SCHEMBL6702896 | 0.85 | MAPT (0.34) | CHRM4MAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL7686588 | 0.84 | F10 (0.36) | CHRM4MAPTALDH1A1LMNATP53 | |
| SCHEMBL6704664 | 0.83 | SAE1 (0.33) | CHRM4MAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL6702793 | 0.83 | MAPT (0.37) | MAPTALDH1A1GAATP53DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |