Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PLTP | P55058 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HK1 | P19367 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705254 | 0.94 | TRPV4 (0.33) | MAPTTRPV4ALDH1A1HPGDPLTP | |
| SCHEMBL6702441 | 0.89 | MAPT (0.39) | MAPTTRPV4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7682217 | 0.89 | TRPV4 (0.38) | MAPTTRPV4ALDH1A1HPGDPLTP | |
| SCHEMBL6704668 | 0.89 | TRPV4 (0.34) | MAPTTRPV4ALDH1A1HPGDPLTP | |
| SCHEMBL7683689 | 0.89 | TRPV4 (0.35) | MAPTTRPV4PLTPLMNASAE1 | |
| SCHEMBL6703995 | 0.88 | MAPT (0.41) | MAPTTRPV4ALDH1A1HPGDPLTP | |
| SCHEMBL7679779 | 0.86 | TRPV4 (0.37) | TRPV4PLTPSAE1UBA2GAA | |
| SCHEMBL6702895 | 0.85 | CHRM4 (0.35) | MAPTALDH1A1CHRM4HSD17B10LMNA | |
| SCHEMBL6700555 | 0.85 | TRPV4 (0.35) | MAPTTRPV4ALDH1A1HPGDPLTP | |
| SCHEMBL7686591 | 0.84 | TRPV4 (0.36) | MAPTTRPV4ALDH1A1HPGDPLTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |