Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703028 | 0.86 | TRPV4 (0.36) | MAPTTP53TRPV4SCDGAA | |
| SCHEMBL6703026 | 0.82 | MAPT (0.34) | MAPTTP53TRPV4SCDALDH1A1 | |
| SCHEMBL7086912 | 0.81 | SCD (0.36) | MAPTTP53TRPV4SCDALDH1A1 | |
| SCHEMBL6703565 | 0.81 | TRPV4 (0.35) | MAPTTP53TRPV4SCDALDH1A1 | |
| SCHEMBL6702802 | 0.80 | GAA (0.39) | MAPTTP53TRPV4GAAALDH1A1 | |
| SCHEMBL6701383 | 0.79 | SAE1 (0.34) | MAPTTRPV4ALDH1A1KDM4EKMT2A | |
| SCHEMBL27581054 | 0.78 | TRPV4 (0.34) | MAPTTP53TRPV4SCDKMT2A | |
| SCHEMBL1008694 | 0.77 | TRPV4 (0.36) | MAPTTP53TRPV4GAAKMT2A | |
| SCHEMBL29403637 | 0.77 | TRPV4 (0.36) | MAPTTP53TRPV4GAAKMT2A | |
| SCHEMBL6703562 | 0.76 | MAPT (0.33) | MAPTTP53TRPV4SCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |