Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702299 | 0.86 | TRPV4 (0.38) | SCDMEN1CCKARKMT2AMAPT | |
| SCHEMBL7091394 | 0.83 | MAPT (0.34) | MEN1CCKARKMT2AMAPTTP53 | |
| SCHEMBL7086907 | 0.82 | F10 (0.38) | SCDMEN1CCKARKMT2AMAPT | |
| SCHEMBL6703035 | 0.81 | MAPT (0.34) | SCDMEN1KMT2AMAPTTRPV4 | |
| SCHEMBL6702802 | 0.78 | GAA (0.39) | MEN1KMT2AMAPTTRPV4TP53 | |
| SCHEMBL7682217 | 0.78 | TRPV4 (0.38) | MEN1CCKARKMT2AMAPTTRPV4 | |
| SCHEMBL7679717 | 0.77 | MEN1 (0.40) | MEN1CCKARKMT2AMAPTTRPV4 | |
| SCHEMBL7087093 | 0.73 | MAPT (0.39) | MEN1KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL6703565 | 0.73 | TRPV4 (0.35) | SCDKMT2AMAPTTRPV4TP53 | |
| SCHEMBL7679713 | 0.73 | MEN1 (0.40) | MEN1CCKARKMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |