Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704444 | 0.89 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL6705427 | 0.88 | MAPT (0.51) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL6704097 | 0.87 | KIF11 (0.53) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL6702824 | 0.87 | KIF11 (0.53) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL6701909 | 0.87 | MAPT (0.59) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL6644510 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL6648013 | 0.83 | GAA (0.46) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL6703161 | 0.83 | RAD51 (0.50) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL6703556 | 0.81 | MAPT (0.46) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL6702073 | 0.81 | RAD51 (0.49) | ALDH1A1MAPTKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116417-A1 | Thiohydantoins and use thereof for treating diabetes | LABORATOIRES FOURNIER SA (FR) | 2004-06-17 | — | — | US | disclosed |
| US-20040013876-A1 | Process for producing reinforcing sic fiber for sic composite material | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-01-22 | — | — | US | disclosed |