Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704097 | 0.89 | KIF11 (0.53) | RAD51AKR1C3MAPTSMN1; SMN2KIF11 | |
| SCHEMBL6702824 | 0.89 | KIF11 (0.53) | RAD51AKR1C3MAPTSMN1; SMN2KIF11 | |
| SCHEMBL6704444 | 0.88 | ALDH1A1 (0.51) | AKR1C3MAPTSMN1; SMN2KIF11ALDH1A1 | |
| SCHEMBL6703556 | 0.88 | MAPT (0.46) | AKR1C3MAPTSMN1; SMN2KIF11ALDH1A1 | |
| SCHEMBL6699022 | 0.88 | KIF11 (0.54) | MAPTPRKDCKIF11ALDH1A1HPGD | |
| SCHEMBL6703729 | 0.88 | PARP1 (0.42) | MAPTSMN1; SMN2KIF11ALDH1A1HPGD | |
| SCHEMBL6703990 | 0.85 | ALDH1A1 (0.51) | AKR1C3MAPTSMN1; SMN2PRKDCALDH1A1 | |
| SCHEMBL6705448 | 0.85 | ALDH1A1 (0.42) | MAPTSMN1; SMN2KIF11ALDH1A1HPGD | |
| SCHEMBL6703161 | 0.84 | RAD51 (0.50) | RAD51MAPTKIF11ALDH1A1GAA | |
| SCHEMBL6704313 | 0.83 | AKR1C3 (0.50) | AKR1C3MAPTSMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116417-A1 | Thiohydantoins and use thereof for treating diabetes | LABORATOIRES FOURNIER SA (FR) | 2004-06-17 | — | — | US | disclosed |