Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.51 |
| ▸ | CCR2 | P41597 | 4/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RHEB | Q15382 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703005 | 0.85 | F10 (0.54) | F10F2 | |
| SCHEMBL14122151 | 0.81 | TDP1 (0.59) | MAPTALDH1A1GAAPKMTHRB | |
| SCHEMBL6703954 | 0.77 | CCR2 (0.47) | F10CCR2MAPTGAALOXL2 | |
| SCHEMBL6703577 | 0.75 | HSD17B10 (0.48) | CCR2MAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL14121922 | 0.72 | TDP1 (0.56) | F10MAPTALDH1A1GAA | |
| SCHEMBL6435704 | 0.71 | F10 (0.73) | F10CCR2F2 | |
| SCHEMBL12822646 | 0.71 | FOLH1 (0.52) | F10 | |
| SCHEMBL12822364 | 0.70 | F10 (0.55) | F10LOXL2ABHD6CYP4F2CYP4A11 | |
| SCHEMBL30417904 | 0.70 | F10 (0.55) | F10LOXL2ABHD6CYP4F2CYP4A11 | |
| SCHEMBL8762311 | 0.69 | MAPK8 (0.48) | F10LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |