Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702995 | 0.82 | HSD17B10 (0.42) | HSD17B10MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13100003 | 0.78 | KDM4E (0.48) | HSD17B10MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6703456 | 0.77 | GPR35 (0.51) | HSD17B10MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6702333 | 0.76 | GPR35 (0.47) | HSD17B10MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6703408 | 0.76 | MAPT (0.58) | HSD17B10MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6703370 | 0.75 | F10 (0.51) | MAPTALDH1A1SMN1; SMN2GAACCR2 | |
| SCHEMBL2476665 | 0.73 | CCR2 (0.60) | ALDH1A1KDM4ESMN1; SMN2TSHRKMT2A | |
| SCHEMBL6703464 | 0.73 | KDM4E (0.62) | HSD17B10MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6740765 | 0.73 | RAB9A (0.42) | HSD17B10ALDH1A1KDM4ECCR2 | |
| Hydrochloric Acid SCHEMBL9085791 | 0.72 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |