SCHEMBL6703569

SCHEMBL6703569

COc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1C#N

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 18/20 0.46
BCAT2 O15382 13/20 0.46
PRKDC P78527 1/20 0.35
AR P10275 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6242603 0.89 BCAT1 (0.54) BCAT1BCAT2AR
SCHEMBL6696927 0.88 BCAT2 (0.43) BCAT1BCAT2
SCHEMBL6698531 0.88 BCAT2 (0.44) BCAT1BCAT2AR
SCHEMBL8914465 0.88 BCAT1 (0.37) BCAT1BCAT2PRKDC
SCHEMBL7742111 0.88 BCAT1 (0.45) BCAT1BCAT2AR
SCHEMBL6697539 0.87 BCAT1 (0.51) BCAT1BCAT2
SCHEMBL8193759 0.87 BCAT2 (0.40) BCAT1BCAT2AR
SCHEMBL6248581 0.86 BCAT1 (0.54) BCAT1BCAT2AR
SCHEMBL6694518 0.86 BCAT2 (0.45) BCAT1BCAT2AR
SCHEMBL6701041 0.85 BCAT2 (0.42) BCAT1BCAT2PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040171488-A1 N-aryl-uracils based Herbicides FEUCHT DIETER (DE) 2004-09-02 US disclosed
US-6734139-B1 N-aryl-uracile-based herbicides BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US disclosed
US-6495491-B1 HERBICIDES AND INSECTICIDES; DEFOLIANTS, DESICCANTS, HAULM KILLERS AND ESPECIALLY WEED KILLERS BAYER AKTIENGESELLSCHAFT (DE) 2002-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171488-A1 N-aryl-uracils based Herbicides DDT, UNG, DDC BCAT1 475/4885BCAT2 552/4885PRKDC 1182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.