Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6792658 | 1.00 | KDM4E (0.31) | KDM4EKDM6BKDM1AMAOAMAOB | |
| SCHEMBL6705035 | 0.90 | FAAH (0.33) | FAAH | |
| SCHEMBL6705040 | 0.90 | FAAH (0.33) | FAAH | |
| Trifluoroacetic Acid SCHEMBL6704433 | 0.89 | KDM4E (0.30) | KDM4EKDM6BKDM1AMAOAMAOB | |
| SCHEMBL4773141 | 0.79 | FFAR1 (0.36) | — | |
| Trifluoroacetic Acid SCHEMBL6781867 | 0.78 | CHRNB2 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL6703829 | 0.78 | CHRNB2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL3526047 | 0.77 | FFAR1 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL6785439 | 0.77 | — | — | |
| Trifluoroacetic Acid SCHEMBL6705344 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794405-B2 | Alicyclic imidazoles as H3 agents | MERCK & CO., INC. | 2004-09-21 | — | — | US | disclosed |
| US-20040029943-A1 | Novel alicylic imidazoles as H3 agents | MERCK SHARP & DOHME CORP. | 2004-02-12 | — | — | US | disclosed |
| US-20020042400-A1 | Novel alicyclic imidazoles as H3 agents | GLIATECH, INC. | 2002-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029943-A1 | Novel alicylic imidazoles as H3 agents | HRH3, HRH2, HRH4 | KDM4E 1995/4885KDM6B 1617/4885KDM1A 1091/4885 |
| US-20020042400-A1 | Novel alicyclic imidazoles as H3 agents | HRH3, HRH2, HRH4 | KDM4E 1664/4885KDM6B 2219/4885KDM1A 1130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.