Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6703765 | 1.00 | KDM4E (0.31) | KDM4EKDM6BKDM1AMAOAMAOB | |
| SCHEMBL6705035 | 0.90 | FAAH (0.33) | FAAH | |
| SCHEMBL6705040 | 0.90 | FAAH (0.33) | FAAH | |
| Trifluoroacetic Acid SCHEMBL6704433 | 0.89 | KDM4E (0.30) | KDM4EKDM6BKDM1AMAOAMAOB | |
| SCHEMBL4773141 | 0.79 | FFAR1 (0.36) | — | |
| Trifluoroacetic Acid SCHEMBL6781867 | 0.78 | CHRNB2 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL6703829 | 0.78 | CHRNB2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL3526047 | 0.77 | FFAR1 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL6785439 | 0.77 | — | — | |
| Trifluoroacetic Acid SCHEMBL6705344 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794405-B2 | Alicyclic imidazoles as H3 agents | MERCK & CO., INC. | 2004-09-21 | — | — | US | disclosed |