SCHEMBL670389

SCHEMBL670389

CCCc1cccc(-c2cccc(CCC)c2O)c1O

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.51
CTSG P08311 5/20 0.51
GABRA1 P14867 3/20 0.50
GABRB2 P47870 3/20 0.50
IAPP P10997 4/20 0.46
ALOX5 P09917 1/20 0.46
PTGS2 P35354 1/20 0.46
PRKCI P41743 1/20 0.44
DAO P14920 1/20 0.39
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28161120 0.90 ELANE (0.53) ELANECTSGGABRA1GABRB2IAPP
SCHEMBL674691 0.88 GABRA1 (0.64) ELANECTSGGABRA1GABRB2IAPP
SCHEMBL8379462 0.87 ALDH1A1 (0.45) ELANECTSGGABRA1GABRB2IAPP
SCHEMBL2467818 0.87 ALOX5 (0.56) ELANECTSGGABRA1GABRB2IAPP
SCHEMBL11611357 0.86 PDCD1 (0.50) ELANECTSGGABRA1GABRB2IAPP
SCHEMBL31376379 0.86 GABRA1 (0.61) ELANECTSGGABRA1GABRB2IAPP
SCHEMBL10523840 0.85 ALOX5 (0.64) ELANECTSGIAPPALOX5PTGS2
SCHEMBL5588855 0.82 ELANE (0.49) ELANECTSGGABRA1GABRB2IAPP
SCHEMBL68921 0.82 IAPP (0.65) ELANECTSGGABRA1GABRB2IAPP
SCHEMBL1005366 0.82 GABRA1 (0.77) ELANECTSGGABRA1GABRB2IAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2948220-B1 PROCESSES FOR MAKING MAGNOLOL DERIVATIVES COLGATE PALMOLIVE CO (US) 2018-07-04 EP claimed
US-9676690-B2 Processes for making magnolol derivatives COLGATE-PALMOLIVE COMPANY (US) 2017-06-13 US claimed
US-20150361017-A1 Processes for Making Magnolol Derivatives COLGATE-PALMOLIVE COMPANY (US) 2015-12-17 US claimed
EP-2948220-A1 PROCESSES FOR MAKING MAGNOLOL DERIVATIVES Colgate-Palmolive Company (US) 2015-12-02 EP claimed
EP-2794535-A1 PROCESSES FOR MAKING MAGNOLOL ANALOGS Colgate-Palmolive Company (US) 2014-10-29 EP claimed
WO-2014115156-A1 PROCESSES FOR MAKING MAGNOLOL DERIVATIVES COLGATE-PALMOLIVE COMPANY (US) 2014-07-31 WO claimed
WO-2013095364-A1 PROCESSES FOR MAKING MAGNOLOL ANALOGS COLGATE-PALMOLIVE COMPANY (US) 2013-06-27 WO claimed
CN-111356434-B Composition comprising an oil and a polyion complex comprising a cellulose-based cationic polymer having at least one fatty chain 莱雅公司 2023-10-20 CN disclosed
CN-116617116-A Combination of polyion complex particles and non-polymeric acids having two or more acid dissociation constants 莱雅公司 2023-08-22 CN disclosed
US-20230149958-A1 DEVICE FOR SUPPLYING A COMPOSITION TO A PRESSURIZED DEPOSITION SYSTEM JOHNSON & JOHNSON CONSUMER INC. (US) 2023-05-18 US disclosed
CN-115484924-A Hyaluronic acid production promoter and collagen production promoter 株式会社资生堂 2022-12-16 CN disclosed
CN-108367175-B Combination of polyion composite particles and hydrophilic or water-soluble UV filters 莱雅公司 2021-07-30 CN disclosed
CN-111356434-A Composition comprising an oil and a polyionic complex comprising a cellulose-based cationic polymer having at least one fatty chain 莱雅公司 2020-06-30 CN disclosed
EP-2605835-A2 COMPOSITIONS COMPRISING PAULOWNIN AND/OR PAULOWNIA EXTRACTS AND USES THEREOF Johnson & Johnson Consumer Companies Inc. (US) 2013-06-26 EP disclosed
EP-2605749-A2 COMPOSITIONS COMPRISING PAULOWNIN AND/OR PAULOWNIA EXTRACTS AND USES THEREOF Johnson & Johnson Consumer Companies Inc. (US) 2013-06-26 EP disclosed
WO-2013036229-A1 ORAL AND SKIN CARE COMPOSITIONS BASED ON A 3, 3 ' - DIALKYL - 1, 1 ' - BIPHENYL - 2, 2 ' - DIOL OR A 3, 3 ' -DIALKENYL- 1, 1 ' -BIPHENYL- 2, 2 ' -DIOL COLGATE-PALMOLIVE COMPANY (US) 2013-03-14 WO disclosed
WO-2012024399-A2 COMPOSITIONS COMPRISING PAULOWNIN AND/OR PAULOWNIA EXTRACTS AND USES THEREOF JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2012-02-23 WO disclosed
WO-2012024392-A2 COMPOSITIONS COMPRISING PAULOWNIN AND/OR PAULOWNIA EXTRACTS AND USES THEREOF JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2012-02-23 WO disclosed
WO-2012024395-A2 COMPOSITIONS COMPRISING PAULWNIN AND/OR PAULOWNIA EXTRACTS AND USES THEREOF JOHNSON & JOHNSON CONSUMER COMPANIES INC. (US) 2012-02-23 WO disclosed
WO-2012024394-A2 COMPOSITIONS COMPRISING PAULOWNIN AND/OR PAULOWNIA EXTRACTS AND USES THEREOF JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2012-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150361017-A1 Processes for Making Magnolol Derivatives CYP4A11, CYP11B1, CYP3A4 ELANE 4428/4885CTSG 3526/4885GABRA1 1352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.