Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B4 | P51659 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699001 | 0.97 | LMNA (0.46) | HPGDSALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL6704475 | 0.75 | LMNA (0.49) | ALDH1A1HPGDKMT2ALMNAHTT | |
| SCHEMBL6701422 | 0.73 | HPGD (0.46) | HPGDSALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL6700774 | 0.70 | HPGD (0.46) | ALDH1A1HPGDKMT2ATSHRMAPT | |
| SCHEMBL5261044 | 0.65 | LMNA (0.44) | ALDH1A1KMT2ALMNAMAPTL3MBTL1 | |
| SCHEMBL21738902 | 0.65 | HPGDS (0.50) | HPGDSALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL28695962 | 0.64 | LMNA (0.86) | HPGDSALDH1A1KMT2ALMNATSHR | |
| SCHEMBL7615473 | 0.63 | LMNA (0.54) | HPGDSALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL1386995 | 0.62 | HPGDS (0.58) | HPGDSALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL1799045 | 0.62 | HPGDS (0.53) | HPGDSALDH1A1HPGDKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102488-A1 | Butenolide and pentenolide derivatives as kinase inhibitors | MORPHOCHEM AG (DE) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102488-A1 | Butenolide and pentenolide derivatives as kinase inhibitors | MAP3K20, MAP3K21, MAP3K1 | HPGDS 998/4885ALDH1A1 2905/4885HPGD 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.