Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760215 | 0.84 | ALDH1A1 (0.50) | NR3C2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL2616115 | 0.84 | L3MBTL1 (0.57) | NR3C2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL31656235 | 0.84 | L3MBTL1 (0.57) | NR3C2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL5713274 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTL3MBTL1LMNANPC1 | |
| SCHEMBL25410674 | 0.82 | NR3C2 (0.43) | NR3C2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL5428356 | 0.82 | ALDH1A1 (0.47) | NR3C2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL6759109 | 0.82 | GAA (0.56) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL16423530 | 0.81 | ALDH1A1 (0.51) | NR3C2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL6760208 | 0.80 | ALDH1A1 (0.46) | NR3C2ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL751610 | 0.79 | NR1H4 (0.59) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002493-A1 | Benzoic acid derivatives and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-01-01 | — | — | US | disclosed |
| EP-1314719-A1 | BENZOIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002493-A1 | Benzoic acid derivatives and pharmaceutical agents comprising the same as active ingredient | PTGER1, PTGER4, PTGES | NR3C2 412/4885ALDH1A1 408/4885MAPT 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.