Pyrrolidine

Pyrrolidine

SCHEMBL6704549

C1CCNC1.CC(=O)CC(N)=O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
CYP2D6 P10635 1/20 0.33
CHRM5 P08912 1/20 0.32
CHRM3 P20309 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
ALOX15 P16050 2/20 0.30
LMNA P02545 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL3834380 0.80
SCHEMBL21332235 0.80 LMNA (0.47) KDM4EALDH1A1MAPTMGAMGAA
SCHEMBL52890 0.80
Pyrrolidine SCHEMBL28213593 0.79 ALDH1A1 (0.48) KDM4EKMT2AALDH1A1MAPTATM
Piperidine SCHEMBL63825 0.78 ALDH1A1 (0.53) KDM4EKMT2AALDH1A1MAPTATM
Pyrrolidine SCHEMBL27400792 0.78 LMNA (0.47) KDM4EKMT2AALDH1A1MAPTATM
Acetoacetic Acid SCHEMBL28315277 0.77 ALDH1A1 (0.41) KDM4EALDH1A1CHRM5CHRM3MGAM
SCHEMBL25275469 0.77
Iodide SCHEMBL31148880 0.77
SCHEMBL1396199 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004027172-A CURING ASSISTING COMPOUND FOR FREE-RADICAL CURABLE RESIN COMPOSITION, FREE-RADICAL CURABLE RESIN COMPOSITION CONTAINING IT, AND METHOD FOR CURING THE RESIN COMPOSITION DJK KENKYUSHO:KK 2004-01-29 JP disclosed
US-20030013789-A1 Process for producing oligo (meth) acrylate-containing resin composition, catalyst for use therein and oligo (meth acrylate-containing resin composition obtained thereby DJK LABORATORIES INC. 2003-01-16 US disclosed