Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704475 | 0.87 | LMNA (0.49) | NPC1RAB9AEPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6703580 | 0.87 | GAA (0.49) | NPC1RAB9AEPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6703296 | 0.84 | RAB9A (0.52) | NPC1RAB9AEPHX1ALDH1A1POLB | |
| SCHEMBL6703375 | 0.72 | TP53 (0.43) | ALDH1A1SMN1; SMN2MAPTHPGDCNR1 | |
| SCHEMBL8303337 | 0.67 | EPHX1 (0.77) | NPC1RAB9AL3MBTL1EPHX1ALDH1A1 | |
| SCHEMBL12784752 | 0.66 | ALOX12 (0.51) | NPC1RAB9AL3MBTL1EPHX1ALDH1A1 | |
| SCHEMBL23130338 | 0.64 | POLB (1.00) | NPC1RAB9AEPHX1ALDH1A1POLB | |
| SCHEMBL10089307 | 0.64 | EPHX1 (1.00) | NPC1RAB9AEPHX1ALDH1A1CYP2C9 | |
| SCHEMBL28603629 | 0.64 | EPHX1 (0.63) | NPC1RAB9AEPHX1ALDH1A1POLB | |
| SCHEMBL13307754 | 0.64 | CNR1 (0.55) | NPC1RAB9AL3MBTL1EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102488-A1 | Butenolide and pentenolide derivatives as kinase inhibitors | MORPHOCHEM AG (DE) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102488-A1 | Butenolide and pentenolide derivatives as kinase inhibitors | MAP3K20, MAP3K21, MAP3K1 | NPC1 3108/4885RAB9A 3482/4885L3MBTL1 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.