Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49544 | 0.86 | CA1 (0.58) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL18224 | 0.80 | CYP3A4 (1.00) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL12189844 | 0.79 | CYP3A4 (0.43) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL31218467 | 0.79 | ALDH1A1 (0.52) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL17659001 | 0.79 | ALOX5 (0.52) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL2044956 | 0.79 | ALDH1A1 (0.52) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL9615644 | 0.79 | CA1 (0.65) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL10546483 | 0.77 | CYP3A4 (0.93) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL4340169 | 0.77 | CYP3A4 (0.93) | CYP3A4TSHRTDP1GABRA1GABRB1 | |
| SCHEMBL11020186 | 0.77 | CYP3A4 (0.93) | CYP3A4TSHRTDP1GABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243126-B1 | METHOD OF MEASURING HYDROGEN PEROXIDE OR OF MEASURING AN ENZYME OR BIOCHEMICAL SUBSTRATE LIBERATING THE PEROXIDE | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1992-08-12 | — | — | EP | claimed |
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-01-02 | — | — | US | disclosed |
| WO-2017159484-A1 | 2,4-DIAMINOPHENOL DERIVATIVE, AND AGENT FOR INHIBITING AGGREGATION OF TAU AND/OR AMYLOID β | 学校法人同志社 | 2017-09-21 | — | — | WO | disclosed |
| WO-2016193136-A1 | HALOGENATED SALICYLANILIDES FOR TREATING CLOSTRIDIUM INFECTIONS | ANTIBIOTX APS (DK) | 2016-12-08 | — | — | WO | disclosed |
| WO-2016051799-A1 | 2-AMINOHYDROQUINONE DERIVATIVE AND TAU AGGREGATION INHIBITOR | 学校法人同志社 | 2016-04-07 | — | — | WO | disclosed |
| EP-2605658-B1 | SPIROXAZOLIDINONE COMPOUNDS | MERCK SHARP & DOHME (US) | 2016-03-23 | — | — | EP | disclosed |
| US-8742110-B2 | Spiroxazolidinone compounds | MERCK SHARP & DOHME CORP. (US) | 2014-06-03 | — | — | US | disclosed |
| US-8716491-B2 | Benzimidazolium dyes and their use as fluorescent chemosensors | NEW YORK UNIVERSITY (US) | 2014-05-06 | — | — | US | disclosed |
| EP-2605658-A1 | SPIROXAZOLIDINONE COMPOUNDS | Merck Sharp & Dohme Corp. (US) | 2013-06-26 | — | — | EP | disclosed |
| US-20130131042-A1 | SPIROXAZOLIDINONE COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | US | disclosed |
| US-4333759-A | Herbicidal 5-cyano-2,3-dihydro-benzofuran-2-ones | FISONS LIMITED (GB) | 1982-06-08 | — | — | US | disclosed |
| US-4274998-A | Diester of 3,5,3',5'-tetrabromo-bisphenol A with halogenated aromatic carboxylic acid | ASAHI-DOW LIMITED (JP) | 1981-06-23 | — | — | US | disclosed |
| US-4263037-A | 5-Cyano-2,3-dihydrobenzofurans useful as herbicides | FISONS LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |
| US-4125628-A | FORMALDEHYDE, QUATERNARY AMMONIUM SALT | VINELAND LABORATORIES, INC. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4079035-A | Halophenoxyphosphazene fire retardants and polyesters containing same | ETHYL CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
| US-4026964-A | Halophenoxyphosphazene fire retardants and polyesters containing same | ETHYL CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |
| US-4022911-A | Disinfectant composition comprising a quaternary ammonium compound, a phenol, and formaldehyde | DAMON CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-4010252-A | POLYQUATERNARY AMMONIUM COMPOUND, DEODORANTS | COLGATE-PALMOLIVE COMPANY (US) | 1977-03-01 | — | — | US | disclosed |
| US-3996312-A | CROSSLINKED BY A PHOSPHORUS-OXYGEN-PHOSPHORUS BOND | ETHYL CORPORATION (US) | 1976-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858880-B2 | Anti-fungals compounds targeting the synthesis of fungal sphingolipids | ERG28, UGCG, DPM1 | CYP3A4 3930/4885TSHR 4805/4885TDP1 3780/4885 |
| US-20130131042-A1 | SPIROXAZOLIDINONE COMPOUNDS | SSTR5, SSTR2, SSTR4 | CYP3A4 2866/4885TSHR 44/4885TDP1 3984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.