SCHEMBL670493

SCHEMBL670493

COC(=O)[C@@H]1C[C@@H](N)CN1C(=O)OC(C)(C)C

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 4/20 0.65
MMP2 P08253 4/20 0.65
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
NR1H2 P55055 2/20 0.41
NR1H3 Q13133 1/20 0.41
PTPN1 P18031 1/20 0.40
ALDH1A1 P00352 1/20 0.39
HTRA1 Q92743 1/20 0.37
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
P2RX3 P56373 1/20 0.35
PEPD P12955 2/20 0.35
PDE4B Q07343 1/20 0.35
HSD17B10 Q99714 1/20 0.35
XPNPEP1 Q9NQW7 1/20 0.34
MMP1 P03956 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2328122 1.00 ANPEP (0.65) ANPEPMMP2CYP1A2POLBCYP3A4
SCHEMBL489156 1.00 ANPEP (0.65) ANPEPMMP2CYP1A2POLBCYP3A4
SCHEMBL1267438 1.00 ANPEP (0.65) ANPEPMMP2CYP1A2POLBCYP3A4
SCHEMBL1267008 1.00 ANPEP (0.65) ANPEPMMP2CYP1A2POLBCYP3A4
SCHEMBL670494 1.00 ANPEP (0.65) ANPEPMMP2CYP1A2POLBCYP3A4
SCHEMBL25181712 1.00 ANPEP (0.65) ANPEPMMP2CYP1A2POLBCYP3A4
SCHEMBL1545946 1.00 ANPEP (0.65) ANPEPMMP2CYP1A2POLBCYP3A4
SCHEMBL7729511 1.00 ANPEP (0.65) ANPEPMMP2CYP1A2POLBCYP3A4
Hydrochloric Acid SCHEMBL1412084 0.98 ANPEP (0.63) ANPEPMMP2CYP1A2POLBCYP3A4
Hydrochloric Acid SCHEMBL2347422 0.98 ANPEP (0.63) ANPEPMMP2CYP1A2POLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106389-A1 NMT INHIBITOR AND USE THEREOF 주식회사 이노보테라퓨틱스 2026-05-21 WO disclosed
WO-2026085629-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2026-04-30 WO disclosed
EP-4540267-B1 CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA MERCK SHARP & DOHME LLC (US) 2026-04-15 EP disclosed
EP-4678238-A2 ARGINASE INHIBITORS AND METHODS OF USE THEREOF Astrazeneca AB (SE) 2026-01-14 EP disclosed
US-20250340548-A1 KRAS G12C INHIBITORS FRONTIER MEDICINES CORP (US) 2025-11-06 US disclosed
US-20250313578-A1 Arginase Inhibitors and Methods of Use Thereof ASTRAZENECA AB (SE) 2025-10-09 US disclosed
EP-3752251-B1 ARGINASE INHIBITORS AND METHODS OF USE THEREOF ASTRAZENECA AB (SE) 2025-09-10 EP disclosed
EP-4565590-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Kumquat Biosciences Inc. (US) 2025-06-11 EP disclosed
US-12291539-B2 KRAS G12C inhibitors FRONTIER MEDICINES CORPORATION (US) 2025-05-06 US disclosed
CN-119866342-A Cyclic peptides for capturing interleukin-1 beta 默沙东有限责任公司 2025-04-22 CN disclosed
US-6399629-B1 PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY MICROCIDE PHARMACEUTICALS, INC. 2002-06-04 US disclosed
WO-2000001714-A1 EFFLUX PUMP INHIBITORS MICROCIDE PHARMACEUTICALS, INC. (US) 2000-01-13 WO disclosed
EP-0367130-B1 Pyrrolidine derivatives FUJISAWA PHARMACEUTICAL CO (JP) 1996-10-02 EP disclosed
US-5514701-A Pyrrolidine derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-05-07 US disclosed
US-5264453-A Pyrrolidine derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-11-23 US disclosed
EP-0289911-B1 PYRROLIDINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-06-16 EP disclosed
US-5130323-A PYRROLIDINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-14 US disclosed
EP-0367130-A2 Pyrrolidine derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-05-09 EP disclosed
US-4916152-A THROMBOXANE A2 ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-04-10 US disclosed
EP-0289911-A2 Pyrrolidine derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313578-A1 Arginase Inhibitors and Methods of Use Thereof ARG1, ARG2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 ANPEP 1703/4885MMP2 999/4885CYP1A2 234/4885
US-12291539-B2 KRAS G12C inhibitors KRAS, NRAS, HRAS ANPEP 4001/4885MMP2 2455/4885CYP1A2 4759/4885
US-20250340548-A1 KRAS G12C INHIBITORS KRAS, NRAS, HRAS ANPEP 4001/4885MMP2 2455/4885CYP1A2 4759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.