Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83772 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL27188439 | 0.78 | — | — | |
| Diethylamine SCHEMBL7707798 | 0.75 | — | — | |
| SCHEMBL14865592 | 0.74 | — | — | |
| SCHEMBL3254849 | 0.73 | — | — | |
| Diethylamine SCHEMBL538119 | 0.71 | — | — | |
| Diethylamine SCHEMBL28341722 | 0.71 | TP53 (0.89) | TP53 | |
| Diethylamine SCHEMBL27752183 | 0.71 | — | — | |
| Diethylamine SCHEMBL5142450 | 0.71 | TP53 (0.50) | TP53 | |
| SCHEMBL28476315 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040192962-A1 | Process for the synthesis of enantiomerically pure cyclohexylphenyl glycolic acid | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192962-A1 | Process for the synthesis of enantiomerically pure cyclohexylphenyl glycolic acid | GRHPR, PGD, HPD | TP53 3432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.