Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796417 | 0.84 | ATM (0.50) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL3633864 | 0.81 | ATM (0.51) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL3636909 | 0.78 | CYP1A2 (0.46) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL4372822 | 0.78 | MAOA (0.53) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL3823640 | 0.78 | ATM (0.51) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL3634029 | 0.77 | ATM (0.47) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL15577710 | 0.75 | MAPK1 (0.46) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL31613919 | 0.75 | TACR1 (0.47) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL3638874 | 0.74 | ATM (0.42) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL3641581 | 0.74 | ATM (0.45) | ATML3MBTL1CYP1A2CYP2A6PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014687-A1 | Macrolide antibacterial compounds | ABBOTT LABORATORIES | 2004-01-22 | — | — | US | claimed |
| US-20040014687-A1 | Macrolide antibacterial compounds | ABBOTT LABORATORIES | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014687-A1 | Macrolide antibacterial compounds | MRPL21, NOP2, PIGS | ATM 4352/4885L3MBTL1 353/4885CYP1A2 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.