Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.73 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16750295 | 0.78 | PDE4A (0.48) | CYP19A1KDM4EPOLBMAPTPDE4A | |
| SCHEMBL11082155 | 0.76 | CYP11B1 (1.00) | CYP19A1CYP11B1CYP11B2TBXAS1POLB | |
| SCHEMBL6755429 | 0.74 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2TBXAS1POLB | |
| SCHEMBL11492200 | 0.73 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL16750284 | 0.73 | PDE4A (0.50) | CYP19A1KDM4EPOLBMAPTPDE4A | |
| SCHEMBL6706747 | 0.73 | ALDH1A1 (0.64) | LMNAMAPTTDP1PDE4APDE4B | |
| Hydrochloric Acid SCHEMBL11356743 | 0.73 | CYP19A1 (0.97) | CYP19A1CYP11B1CYP11B2TBXAS1POLB | |
| SCHEMBL5557953 | 0.72 | PDE4A (0.62) | KDM4EPOLBMAPTPDE4APDE4B | |
| SCHEMBL9278001 | 0.70 | PDE4A (0.66) | POLBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL5559147 | 0.70 | PDE4A (0.66) | POLBMAPTPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | YANG JI CHEMICAL COMPANY LTD (KR) | 2004-04-08 | — | — | US | claimed |
| CN-1473160-A | Indole derivatives as medicinal compositions for antifungal and/or antiparasitic agents | 杨池化学有限公司 | 2004-02-04 | — | — | CN | claimed |
| EP-1322638-A1 | ANTIFUNGAL AND/OR ANTIPARASITIC PHARMACEUTICAL COMPOSITION AND NOVEL INDOLE DERIVATIVES AS ACTIVE PRINCIPLE OF SUCH A COMPOSITION | Yang Ji Chemical Company Ltd. (KR) | 2003-07-02 | — | — | EP | claimed |
| WO-2002024685-A1 | INDOLE DERIVATIVES AND THEIR USE AS ANTIFUNGAL AND/OR ANTIPARASITIC AGENTS | YANG JI CHEMICAL COMPANY LTD. (KR) | 2002-03-28 | — | — | WO | claimed |
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | YANG JI CHEMICAL COMPANY LTD (KR) | 2004-04-08 | — | — | US | disclosed |
| CN-1473160-A | Indole derivatives as medicinal compositions for antifungal and/or antiparasitic agents | 杨池化学有限公司 | 2004-02-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | IDO1, IDO2, TPH1 | CYP19A1 1538/4885CYP11B1 202/4885CYP11B2 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.