Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 5/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 5/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 5/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 5/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705572 | 0.86 | PLAAT3 (0.43) | PLAAT3PLAAT5PLAAT2PLAAT4MCHR1 | |
| SCHEMBL5260776 | 0.81 | PLAAT3 (0.48) | PLAAT3PLAAT5PLAAT2PLAAT4ALDH1A1 | |
| SCHEMBL27944339 | 0.80 | PLK4 (0.55) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL17646483 | 0.78 | PLAAT3 (0.48) | PLAAT3PLAAT5PLAAT2PLAAT4ALDH1A1 | |
| SCHEMBL6706859 | 0.78 | MCHR1 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4MCHR1 | |
| SCHEMBL6708022 | 0.77 | L3MBTL1 (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4KDM4E | |
| SCHEMBL17646473 | 0.76 | CNR1 (0.46) | PLAAT3PLAAT5PLAAT2PLAAT4ESRRG | |
| SCHEMBL19376791 | 0.75 | HPGD (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4MCHR1 | |
| SCHEMBL15319511 | 0.75 | CA12 (0.56) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL250873 | 0.73 | PLAAT3 (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678591-A | Novel carboxamide compounds having MCH-antagonistic action, pharmaceutical preparations comprising said compounds and process for their preparation | BOEHRINGER INGELHEIM INT (DE) | 2005-10-05 | — | — | CN | disclosed |
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | PLAAT3 4485/4885PLAAT5 3832/4885PLAAT2 4302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.