Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.71 |
| ▸ | NPC1 | O15118 | 5/20 | 0.71 |
| ▸ | RAB9A | P51151 | 5/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | SLC2A1 | P11166 | 8/20 | 0.65 |
| ▸ | SLC2A3 | P11169 | 8/20 | 0.65 |
| ▸ | SLC2A2 | P11168 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568696 | 0.82 | MAPT (1.00) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL29618261 | 0.82 | MAPT (1.00) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL7658416 | 0.81 | MAPT (0.80) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL2628836 | 0.80 | SLC2A1 (0.77) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL2628843 | 0.80 | MAPT (0.80) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL13390339 | 0.76 | MAPT (0.67) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL13576575 | 0.74 | ALDH1A1 (0.69) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL24533665 | 0.73 | NPC1 (0.78) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL15176822 | 0.73 | ALDH1A1 (0.67) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL23024507 | 0.71 | MAPT (0.59) | MAPTNPC1RAB9AMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815444-B2 | Anti-enterovirus compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2004-11-09 | — | — | US | disclosed |
| US-20040204400-A1 | ANTI-ENTEROVIRUS COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204400-A1 | ANTI-ENTEROVIRUS COMPOUNDS | NR2E1, NR4A1, NR0B1 | MAPT 4721/4885NPC1 1786/4885RAB9A 2934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.