Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.80 |
| ▸ | NPC1 | O15118 | 5/20 | 0.80 |
| ▸ | RAB9A | P51151 | 5/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | SLC2A1 | P11166 | 9/20 | 0.68 |
| ▸ | SLC2A3 | P11169 | 9/20 | 0.68 |
| ▸ | SLC2A2 | P11168 | 8/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568696 | 0.88 | MAPT (1.00) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL29618261 | 0.88 | MAPT (1.00) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL2628836 | 0.82 | SLC2A1 (0.77) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL2628843 | 0.82 | MAPT (0.80) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL6706131 | 0.81 | MAPT (0.71) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL13390339 | 0.78 | MAPT (0.67) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL24533665 | 0.78 | NPC1 (0.78) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL13576575 | 0.77 | ALDH1A1 (0.69) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL7655764 | 0.76 | NSD2 (0.75) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL25211644 | 0.75 | MAPT (0.65) | MAPTNPC1RAB9AMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423716-B1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |