Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 12/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707269 | 0.88 | CFTR (0.46) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL6709030 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL424286 | 0.71 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL6706444 | 0.69 | KDM4E (0.40) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL5419988 | 0.65 | PPARD (0.41) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL2960947 | 0.64 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL424990 | 0.64 | RXRB (0.70) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL17686796 | 0.64 | KDM4E (0.40) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL460066 | 0.64 | KDM4E (0.69) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL18131082 | 0.64 | KDM4E (0.48) | ALDH1A1HPGDKDM4EHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162326-A1 | Substituted aryl ketones | MULLER KLAUS-HELMUT (DE) | 2004-08-19 | — | — | US | disclosed |
| US-6727206-B2 | USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-04-27 | — | — | US | disclosed |
| US-20030228983-A1 | Substituted aryl ketones | MULLER KLAUS-HELMUT (DE) | 2003-12-11 | — | — | US | disclosed |
| US-6610631-B1 | 2-(2-((4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)-sulphanyl) -4-trifluoromethyl-benzoyl)-1,3-cyclohexanedione used as pre-/postemergences herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162326-A1 | Substituted aryl ketones | CYP1A1, CYP1B1, CYP2E1 | ALDH1A1 26/4885HPGD 4186/4885KDM4E 805/4885 |
| US-20030228983-A1 | Substituted aryl ketones | CYP1A1, CYP1B1, CYP2E1 | ALDH1A1 26/4885HPGD 4186/4885KDM4E 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.