SCHEMBL6706514

SCHEMBL6706514

O=c1nc(C2(c3ccccc3)C=CC=CC2)c2c(=O)nc(C3(c4ccccc4)C=CC=CC3)c1=2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2283117 0.78 HDAC4 (0.34)
Ethylene SCHEMBL27402897 0.75 HDAC4 (0.32)
Biphenyl SCHEMBL28885424 0.73 ALDH1A1 (0.36)
SCHEMBL7776293 0.71
SCHEMBL30663214 0.69 KDM1A (0.36)
SCHEMBL4630348 0.69 GRIN2B (0.33)
SCHEMBL11881975 0.68
SCHEMBL30868877 0.68 NPC1 (0.39)
SCHEMBL30940607 0.67 SLC6A2 (0.36)
SCHEMBL27636806 0.66 MTOR (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040194666-A1 Pigment compositions for coatings CIBA SPECIALTY CHEMICALS CORP. 2004-10-07 US claimed
US-20040194666-A1 Pigment compositions for coatings CIBA SPECIALTY CHEMICALS CORP. 2004-10-07 US disclosed
EP-0811625-B1 Process for preparing diketopyrrolopyrrole derivatives CIBA SC HOLDING AG (CH) 2002-04-17 EP disclosed
EP-0811625-A2 Process for preparing diketopyrrolopyrrole derivatives Ciba SC Holding AG (CH) 1997-12-10 EP disclosed