Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 5/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123309 | 0.89 | ADRB2 (0.54) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6213805 | 0.88 | ALDH1A1 (0.56) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL1416412 | 0.84 | ADRB2 (0.49) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL5704356 | 0.83 | GSK3B (0.53) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6213808 | 0.83 | ALDH1A1 (0.43) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7030311 | 0.82 | KDM4E (0.51) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6710683 | 0.82 | KDM4E (0.49) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL27692958 | 0.82 | ALDH1A1 (0.39) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7029929 | 0.81 | ALDH1A1 (0.50) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7646010 | 0.81 | ALDH1A1 (0.47) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040073030-A1 | Process for the preparation of quinolone derivatives | NATCO PHARMA LIMITED (IN) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040073030-A1 | Process for the preparation of quinolone derivatives | CBR1, CYP4X1, NRAS | ALDH1A1 1601/4885POLB 1574/4885OPRM1 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.