Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710683 | 0.89 | KDM4E (0.49) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL7030311 | 0.88 | KDM4E (0.51) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL6710644 | 0.87 | KDM4E (0.54) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL7026023 | 0.86 | KDM4E (0.53) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL6706593 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL1416412 | 0.79 | ADRB2 (0.49) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL27691603 | 0.78 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL9636141 | 0.78 | KDM4E (0.69) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL6708754 | 0.78 | KDM4E (0.80) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL10569538 | 0.77 | KCNH2 (0.69) | ALDH1A1KDM4EHPGDLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282603-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF QUINOLONE DERIVATIVES | Natco Pharma Limited (IN) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001085692-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF QUINOLONE DERIVATIVES | NATCO PHARMA LIMITED (IN) | 2001-11-15 | — | — | WO | disclosed |